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Intrinsic OXPHOS limitations underlie cellular bioenergetics in leukemia.
Nelson MA, McLaughlin KL, Hagen JT, Coalson HS, Schmidt C, Kassai M, Kew KA, McClung JM, Neufer PD, Brophy P, Vohra NA, Liles D, Cabot MC, Fisher-Wellman KH. Nelson MA, et al. Among authors: coalson hs. Elife. 2021 Jun 16;10:e63104. doi: 10.7554/eLife.63104. Elife. 2021. PMID: 34132194 Free PMC article.
Alterations in sphingolipid composition and mitochondrial bioenergetics represent synergistic therapeutic vulnerabilities linked to multidrug resistance in leukemia.
Fisher-Wellman KH, Hagen JT, Kassai M, Kao LP, Nelson MAM, McLaughlin KL, Coalson HS, Fox TE, Tan SF, Feith DJ, Kester M, Loughran TP Jr, Claxton DF, Cabot MC. Fisher-Wellman KH, et al. Among authors: coalson hs. FASEB J. 2022 Jan;36(1):e22094. doi: 10.1096/fj.202101194RRR. FASEB J. 2022. PMID: 34888943 Free PMC article.
Bioenergetic Phenotyping of DEN-Induced Hepatocellular Carcinoma Reveals a Link Between Adenylate Kinase Isoform Expression and Reduced Complex I-Supported Respiration.
McLaughlin KL, Nelson MAM, Coalson HS, Hagen JT, Montgomery MM, Wooten AR, Zeczycki TN, Vohra NA, Fisher-Wellman KH. McLaughlin KL, et al. Among authors: coalson hs. Front Oncol. 2022 Jun 8;12:919880. doi: 10.3389/fonc.2022.919880. eCollection 2022. Front Oncol. 2022. PMID: 35756609 Free PMC article.